The SARS-CoV-2 Infection shows a variety of symptoms, ranging from very mild symptoms to severe diseases. Despite many studies on SARS-CoV-2 infection, there is a lack of research supporting the results of clinical chemistry tests according to symptoms. We report a correlation of clinical chemistry results and symptoms of SARS-CoV-2 infected patient. We conducted a retrospective single-center study of 202 SARS-CoV-2 infection confirmed patients by PCR test at Boramae hospital in Seoul, South Korea. This study enrolled patients confirmed in March to August 2020 and compared clinical symptoms and clinical chemistry results of patients. Enrolled patients were classified into the following symptoms: asymptomatic, fever, cough, sputum, dyspnea, fatigue/general weakness, myalgia, headache/dizziness, loss of taste/smell, sore throat, runny nose, nausea/vomiting, diarrhea, and a history of oxygen therapy, mechanical ventilation shock, extracorporeal membrane oxygenation and intensive care unit. All enrolled patients also had the results of following clinical chemistry: blood urea nitrogen, creatinine, total protein, total bilirubin, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, c-reactive protein, creatine kinase, troponin-I, procalcitonin and ferritin. Being compared to those without specific symptoms, specific symptoms such as fever, cough, sputum, dyspnea, fatigue/general weakness/myalgia and oxygen therapy showed a significant difference in some clinical chemistry results. Asymptomatic infection and loss of taste/smell showed the opposite relationship to other symptoms in some clinical chemistry results. We found that the results of clinical chemistry showed a significant difference according to the symptoms of SARS-CoV-2 infection. Clinical chemical tests have a sufficient role in the symptom management of SARS-CoV-2 infection.